Caffeine may be the most popular legal addictive stimulant that is available to mankind. Besides coffee, tea, guarana and kola nut have excess amount of this xanthine alkaloid, which is actually acting as a psychoactive drug. In several plants, caffeine is an effective insect repellant, but this trimethylxanthine is deemed by the Food and Drug Administration as generally safe food substance. It is an antagonist of adenosine receptors. The effect of caffeine is individual and may more or less increase the ability to perform physical and mental labor. It reduces the effects of fatigue and may in long term help predominantly men reduce the risk of developing Parkinson’s disease. It has also been observed that caffeine has nootropic effects, furthermore, regular consumption of caffeine may significantly reduce the risk of heart diseases.

Cayenne, which contains Capsaicin, a thermogenic substance. A thermogenic raises your core temperature, which allows you to burn more calories from food, particularly when eating a high fat meal.

Hordenine, which is also known as N-Dimethyl-hydroxyphenylethylamine, is a phenylethylamine alkaloid, which naturally occurs in barley seeds, but also in several cactus plants. The phenomenal antibiotic and antibacterial properties have long been recognized by the medical community, where in particular penicillin resistant Staphylococcus bacteria can be successfully restrained. Hordenine stimulates norepinephrine release and is therefore deemed a direct central nervous system stimulant. Norepinephrine, in turn, is a hormone that works as a lipolytic, aiding in liberating the stored fat from the cells and make it available for burning during the workout. The body building community commonly uses Hordenine as a weight loss agent. Furthermore, it seems that Hordenine is slowing down the digestive process, thereby slowing down the calorie transfer, allowing the excess fat to be burned, while retaining the feeling of satiation.

PEA (Phenylethylamine), which is also known as Beta-Phenylethylamine, is a supplement, which favors aggression and is supposed to raise mental alertness, focus, and ability to concentrate. It is believed to also promote energy. In clinical trials it has been observed that infusion of Beta-Phenylethylamine raises the extracellular dopamine count, furthermore inhibiting the dopamine transmitter DA neuron firings. An additional activity is seen through the Beta-Phenylethylamine modulation of noradrenergic transmissions. It is viewed as a stimulant, but the lack or disturbed amounts of PEA have been observed in people with attention deficit and the hyperactivity disorders, people suffering from depression, schizophrenia, migraine and phenylketonuria. The obvious antidepressant qualities are paired with the increased wakefulness, which may lead to difficulty falling asleep, but improve motivation when exercising or training.