5-HTP or 5-Hydroxytryptophan is an amino acid that occurs naturally in the body. It leads to an increase in levels of serotonin - a neurotransmitter which regulates behavior and mood, and melatonin – a hormone linked with the normal sleep pattern. 5-HTP is used in JetFuel because it is known to reduce anxiety and depression as it is an antidepressant. It is used in the treatment of insomnia, migraine and Fibromyalgia which causes pain in the muscles, tendons and ligaments, severe fatigue and disturbed sleep. It also assists weight loss by reducing appetite. It is found in small amounts in cheese and white meat. Using the supplement in excess can cause side effects like heart valve disease, nausea, etc. and hence it is essential to seek medical advice before using it.

Acetyl L-Carnitine is also known as ALCAR, and has been widely popularized as the superior form to L-Carnitine pertaining to the bioavailability. Carnitine is the quaternary ammonium compound which is being used to move fatty acids out of the cytosol and into the mitochondria when the fats are being broken down, when these are needed to generate additional metabolic energy. The biologically active form of Carnitine is L-Carnitine; Acetyl L-Carnitine is the acetylated form of L-Carnitine and is also known as Acetylcarnitine. L-Carnitine is generally derived from lysine and methionine, which are both amino acids. While the neuro-protecting properties of Acetyl L-Carnitine have been tested on lab animals and some proof was obtained, the role of Acetyl L-Carnitine as a weight loss agent still needs some testing in studies on humans.