Caffeine is the most widely used legal stimulant of the central nervous system and is also used in Phenterfein , with characteristics that have been described as restoration of alertness and removing from drowsiness. Coffee, Tea, many soft drinks and energy drinks as well as nutrition supplements have this ingredient, which is a psychoactive substance, a xanthine alkaloid that can act as a adenosine receptor antagonist, as well as a phosphodiesterase inhibitor. Although regular use of caffeine seems to have nootropic effects, enhancing cognitive abilities, it also is known to provide long term effects on the nervous and cardiovascular system, like in one study it was proven that people with normal to low blood pressure have the possibility of developing a heart disease significantly reduced, as well as the chance of getting the Parkinson’s disease.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Evodia Rutaecarpa has been used in China by the native medicine and herbology practitioners for centuries as a weight loss agent. The Tetradium plant, as it is also known, as well as the bee bee tree, is native to Asia and the chemical associated with the weight loss effect has been isolated as evodiamine. In trials on mice it has been proven that the uptake of fat was significantly reduced by the specimen receiving the Evodia Rutaecarpa extract. While human testing was never truly conducted, the use of Evodia Rutaecarpa extracts in weight loss products seems to prove the interaction with the uncoupling protein 1, or UCP1, also named thermogenin. The stimulation of thermogenin by Evodia Rutaecarpa extract leads to energy being burned as heat, burning excess calories and consequently stored fat.

Glucuronolactone is actually short for glucuronic acid lactone, which is naturally occurring in the human body, namely in the liver. According to reports, the United States Government used Glucuronolactone to provide their soldiers in Vietnam with additional energy and a feeling of wellbeing. While there is no confirmation to these claims by the US Government, the characteristics of Glucuronolactone are true and therefore it is a very popular ingredient in energy drinks. Additionally, Glucuronolactone is a very important part of all connective tissues, and is also a known detoxing agent. Being a natural component of the human organism, it is a much better stimulant than caffeine, reducing sleepiness and fatigue, additionally improving concentration and overall mental performance. In Canada and some parts of Europe, Glucuronolactone is a controlled substance.

L-Taurine , which contains cysteine and methoinine is an essential amino acid. It acts as a diuretic by maintaining the level of magnesium and potassium in our cells while purging sodium. It improves the functioning of kidney and gets rid of fluid accumulation and swelling and thus keeps our body away from toxicity. It maintains a good balance of calcium in our body and strenghtens the heart muscles too. L-Taurine is also used in the treatment of progressive eye conditions, hypertension, memory loss, cystic fibrosis and in atherosclerosis. It is often mixed in energy drinks because while working out the level of L-taurine drops in the skeletan muscle, L-taurine supplements lowers the level of exhaustion and improves endurance. Besides being found in meat and egg yolks it is abundantly found in shellfish.

L-Tyrosine is a protein non-essential building block Although non-essential it is important for the structure of body proteins. It has a direct effect on neurotransmitters.

Niacin is an essential B vitamin, in cellular energy used for the promotion of healthy cardiovascular function, nervous system function, and immune function. Niacin nutritionally manages cholesterol levels already within the normal range. Also known as vitamin B3, niacin is one of a complex of B vitamins that are essential for good health. Niacin is so-called nicotinic acid, known also as nicotinamide. It helps regulate blood sugar and also works at cellular level protecting the skin and enhances the digestive system. And being an originator of the amino acid tryptophan, it can be made by tryptophan in the body. It’s also a coenzyme playing an important role in body metabolism. Supplements of vitamin B3 are also known to reduce levels of bad cholesterol and increase good cholesterol in the blood.

Octopamine is related to noradrenaline. Octopamine was discovered by Vittorio Erspamer, an Italian scientist in 1948. Octopamine has a significant role in mollusks and is the central nervous system in snail. Octopamine also has a vital role in memory and learning in the fruit fly and honey bee. Octopamine is also useful for the firefly in releasing the light production. Octopamine mobilizes releasing fat in mammals and this has developed into promotion as a slimming aid on the internet. However, there is no apparent evidence about Octopamine facilitating weight loss. Octopamine also significantly increases the blood pressure in combination with stimulants such as weight loss supplements. This is extensively used in energy demanding insects such as spiders, lobsters, crabs and crayfish as their behaviors also include egg-laying, jumping and flying. Among vertebrates, Octopamine substitutes norepinephrine and as well exhibits common side effects. Octopamine is sited in the locust jump such that it modulates the muscle activity allowing the leg muscles to contract effectively.

Pantothenic Acid is thought to reduce lactic acid accumulation in athletes, may improve oxygen utilization efficiency, and is believed to improve the body's ability to heal and possibly help in reducing acne

Rhodiola , popularly known as the “golden root” in Russia has been considered an effective treatment for stress and depression. This adaptogenic herb enhances resistance without changing the normal biological function of the body. Rhodiola is found in Asia and Europe’s artic areas at high altitudes. Scandinavian and Russian countries have been using its roots to cure poor attention span and fatigue for centuries. Rhodiola rosea is also effective in improving mood by enhancing mental and physical performance. There are several compounds in Rhodiola rosea which makes it so effective. It includes rosavins along with active components like tyrosol and rhodioloside. This supplement is available in the form of tablet or capsules that can be taken once or twice on a daily basis. You can also increase the dosage if needed.

Salvia Sclarea

Thiamine, also called Vitamin B1 or Thiamin, is needed to help the body utilize energy from proteins, fats and carbohydrates. Thiamine is commonly found in breads and cereals. Thiamine is water-soluble and is concentrated in muscle tissue as it passes thru the body.

Vinpocetine- The lesser periwinkle plant named Vinca Minore consists of Vincamine, which is found in its leaves and Vinpocetine is derived from this natural substance found in the plant. In countries such as Japan and Europe, Vinpocetine is a prescribed medicine. It is popularly available in the online stores and countries such as Canada and the US as an effective supplement for diet. Vinpocetine is a great medicine in order to protect oneself from brain dementia. It has also been found to help treat Alzheimer’s disease. However, there is no strong recent evidence to prove its effect on the treatment of Alzheimer’s disease. Overall, it’s great to boost the brain. However, it has certain side effects such as anxiety, insomnia, indigestion, dry mouth, headache and many more.

Vitamin B12, or rather the Vitamin B complex, is a group of vitamins that are all soluble in water and very often coexist in food sources. While every single Vitamin from the B complex group has a name, they are very often referred to by the number added to the Vitamin B group name, like Vitamin B1, which is thiamine, or Vitamin B2, which is riboflavin. Some other compounds have been added to the Vitamin B group at some time, but were later dropped, like adenine, orotic acid or adenosine monophosphate, where later research found that they are either synthesized by the human body or simply no Vitamins. Vitamin B complex supports the metabolism rate, maintains muscle tone and skin, raises functions of the nervous system and the immune system, promotes red blood cells and cell growth and division and much more.

Vitamin B6 allows the metabolism of amino acids, carbohydrates, as well as lipids to take place, also aids in keeping skin vibrant.

Yohimbine HCL, sometimes called yohimbine hydrochloride, yohimbe, or yohimbe bark, is an herbal supplement which serves as a stimulant and possible aphrodisiac for users. Yohimbine has also been shown to be successful in treating erectile dysfunction and impotence in men. It may serve to boost the sex drive of those who take it for aphrodisiac purposes. Some people are recommended to take yohimbine to combat their lower sex drives caused by antidepressants. Yohimbine has also been shown to help blood pressure levels and assist in weight loss. For these reasons, yohimbine is a popular supplement amongst athletes as well as many others wishing to improve their health.