Caffeine is a stimulant that is used to stay awake and it gives mental alertness from fatigue. This is used as an adjunct for pain relief and also as energy accelerates. Caffeine is a non-prescription drug easily available as over the counter medication and comes in combination to acquire relief from headache and pain. Caffeine increases the mental alertness by offering the required energy for exercise training and weight loss. Caffeine cannot be considered as a mere stimulant as it reaches deep into muscles and provides power that is long lasting. Caffeine taken before any work out is also great as it fights the fatigue and keeps the person ready for the workout. Dieters also find caffeine as the solution as they feel sluggish. This is a no-calorie stimulant and does its job effectively and quickly. Caffeine anhydrous is found even in one or two coffee cups. However, this limitation is recommended as excess caffeine may result in irritability, rapid heart beat, nervousness and sleeplessness.

Diiodotyrosine, used by the thyroid hormones T4 and T3, Diiodotyrosine may help the thyroid gland to maintain proper function and help preserve lean muscle and supports the thyroid without suppressing TSH levels.

Evodiamine- Tetradii Fructus, the fruit of the evodia plant, also known as Tetradium rutaecarpa, contains an active element that has recently been identified as evodiamine. This chemical compound is believed to be somewhat similar to capsaicin, the active compound found in the chili peppers. Some studies suggested that this vanilloid receptor agonist may interact with thermogenin, otherwise known as the uncoupling protein 1, UCP1, which is able to generate heat by a mechanism called thermogenesis. Tetradium rutaecarpa has been traditionally used in Chinese medicine for weight loss purposes and current studies seem to verify this information. Evodiamine has been embraced as a dietary supplement directed at weight loss, predominantly by the body building circles. This supplement is deemed to have energy burning and fat reducing, as well as diuretic properties.

Green Tea Extract- For thousands of years, Green Tea has been used for the purpose of medicine in countries such as China and India. The leaves of the Camellia Sinensis plant are allowed to dry after being lightly steamed. The leaves are steamed as the properties of the plant are retained through this procedure. The extract has a number of varying health benefits, inclusive of properties that assist the body in fighting cancer and body protecting antioxidant effects. Green tea also offers protection against digestive and respiratory infections. It reduces health affecting LDL cholesterol, increases the levels of HDL cholesterol that is good for the body. Along with keeping control of the content of blood sugar in the body, it also helps burn fat in the body by boosting the metabolic rates.

Iodotyrosone, which is a form of tyrosine with iodine added.

L-Tyrosine is a non-essential amino acid, which is used by the cells in order to synthesize the proteins and appears to help stabilize ones mood during periods of high stress levels.

Naringin, which is a citrus flavanoid that is found in grapefruit. Naringin is commonly used in energy supplements as it may extend the duration of the effects of caffeine.

Octopamine, which is a trace amine, recently believed to be a lipotropic for fat loss. Octopamine has low oral bioavailability and is readily broken down by MAOI, as well as metabolized by the gut wall, which may mean it would not work well when taken orally, but more research is needed to prove its positive or negative effects.

Synephrine, More commonly called "bitter orange" or Citrus Aurantium, which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Yerba Matte- Described as an ancient drink of friendship derived from a small shrub. It is sometimes spelled as yerba mate and people drink it in order to gain energy producing properties without consuming caffeine as they would in normal tea or coffee. People believe that yerba mate is a appetite suppressant, clears the mind as well as relieving allergies, improving sleep patterns and lifting the mood, that is why it is used in Thermonex EF. It is advertised as an aid to weight loss, a fortifier of the immune system, a colon cleanser and even as a means of extending life. It is prepared as an infusion, with twigs and leaves immersed in boiling water in order to produce a tisane. Traditionally it is made in a vessel which is then shared among friends.